You are sedating a 225g rat with acepromazine and midazolam….

Questions

Yоu аre sedаting а 225g rat with aceprоmazine and midazоlam.  The stock concentration of acepromazine is 10 mg/ml and the stock concentration of midazolam is 50 mg/ml.  You will use, however, diluted concentrations as follows: 0.1% acepromazine solution and 1% midazolam solution.  The doses for rats are: 0.5mg/kg acepromazine and 2mg/kg midazolam.  Round to the hundreths place for all equations. A. You first need to make up 5 ml of each diluted solution.  For both acepromazine and midazolam, determine how much stock solution is needed to make 5ml of the desired diluted solution.  How much sterile diluent will you need for each? answer example: X ml of stock acepromazine; X ml of sterile diluent                                        X ml of stock midazolam; X ml of sterile diluent   B.  Using the diluted solutions, now calculate the volume of each drug you will draw up in your syringe to dose the rat safely.  Remember to watch your units! answer example: X ml of diluted acepromazine solution                                        X ml of diluted midazolam solution

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