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TCR diversity is established as a result of:

Imagine you are a doctor and you discover your infant patient has a missense mutation of the RAG proteins which leads to partial enzymatic activity of RAG enzymes which leads to symptoms that show as autoimmunity.  Based on what we have discussed in class, you conclude that:

MHC Class I presents ____ antigens to ____ T-cells.

TCR diversity is established as a result of:

In which of the following stages of B-cell development would you expect to see the pre-BCR expressed?

During maturation of T and B cells, which of the following enzymes do you expect to see?

What cells would be able to express an MHC presenting a peptide that is 13-25 amino acids in length?

All of the following components form part of the CD3 complex except for:

What cells would be able to express an MHC presenting a peptide that is 13-25 amino acids in length?

TCR molecules and BCR’s both have (complimentary determining regions) CDR’s/HV’s (hypervariable regions).