Non-disjunction is the failure of homologous chromosomes to…

Non-disjunction is the failure of homologous chromosomes to separate during meiosis I, or the failure of sister chromatids to separate during meiosis II or mitosis. As a result, both homologous chromosomes or both sister chromatids migrate to the same pole of the cell. This produces daughter cells with an imbalance of chromosomes. A cell biologist examines the final products of meiosis in an earthworm (2n=36) and finds 2 cells with 20 chromosomes, and 2 cells with 16 chromosomes. Most likely this was because