The radiation (which includes light) that is intercepted by the earth’s magnetic field and ozone (O3)?
Blog
Case study #6 Clostridium botulinum is the causative agent o…
Case study #6 Clostridium botulinum is the causative agent of botulism. This Gram-positive, anaerobic bacillus is commonly found on plants, in soil and water, and in the intestinal tract of some animals. The main virulence factor of C. botulinum is botulism toxin, which is a protein neurotoxin that causes muscle paralysis. Death results from paralysis of respiratory muscles. Genetic analysis has led to the understanding that C. botulinum has acquired its toxin genes from lysogenic bacteriophages. Adults who ingest C. botulinum spores alone generally do not become ill. However, adult botulism will result after ingestion of food containing botulinum toxin. Boiling and common chemical treatments used for water denatures botulism toxin. Infantile botulism, rather, results after children under the age of one ingest foods, such as honey, which contains C. botulinum spores but no botulinum toxin. Once inside the infant gut, these spores germinate and botulism toxin is produced after colonization. Treatment for botulism requires injections of botulinum antitoxin, pre-made antibodies that are administered to the patient as quickly as possible. Botulinum toxin can be best described as a(n)
List two factors that have led to a decline in fertility in…
List two factors that have led to a decline in fertility in the post-WW2 era. Provide a brief economic explanation of how each led to a decline in fertility.
Expert chess players outperform novices in terms of recallin…
Expert chess players outperform novices in terms of recalling piece location for both random and in-play (real) boards.
Expert chess players outperform novices in terms of recallin…
Expert chess players outperform novices in terms of recalling piece location for both random and in-play (real) boards.
Match the class of vaccine to its proper description.
Match the class of vaccine to its proper description.
Case study #1 NDM-1 is an enzyme that hydrolyzes and inactiv…
Case study #1 NDM-1 is an enzyme that hydrolyzes and inactivates nearly all known β-lactam-class antibiotics. This enzyme requires a metallic ion, usually zinc, to catalyze the hydrolysis reaction. The gene encoding NDM-1 is found on a conjugative plasmid and is efficiently transferred to many Gram negative bacteria.
Polio is transmitted by ingestion of water contaminated with…
Polio is transmitted by ingestion of water contaminated with feces containing poliovirus. What kind of transmission does this represent?
Resistance to this hormone would predispose to obesity
Resistance to this hormone would predispose to obesity
Extra credit case study In August 2014, a 68-year-old man su…
Extra credit case study In August 2014, a 68-year-old man sustained a deep bite to his left fourth and fifth fingers from his pet African gray parrot. The gentleman had a past medical history of chronic obstructive pulmonary disease, for which he took regular inhaled steroids. He was also severely affected by osteoarthritis, for which he took long-acting morphine as analgesia. A day following the parrot bite, he saw his family practitioner for a consultation. The practitioner noted a laceration over the fourth proximal interphalangeal phalanx (PIP) with reddening of the surrounding tissues, and a course of oral antibiotics that have a broad spectrum against most Gram positive and Gram negative bacteria was prescribed for a presumed diagnosis of bacterial cellulitis (skin infection)… In October 2015, the patient again visited his general practitioner with worsening fourth finger swelling and erythema and a new fleshy nodule on the dorsal aspect of the left wrist. In November 2015, a rheumatologist injected steroids into the fourth PIP joint. In December 2015, the fourth PIP wound reopened and his entire left hand became red and swollen. The orthopedic team performed an initial washout with debridement, and amputation was considered. In February 2016, a second washout was performed from which deep tissue swabs showed non-nucleated acid-fast bacilli on a smear. A comprehensive medical history taken in February 2016 revealed that, in addition to the African gray parrot, the patient kept tropical fish and had cleaned the fish tank thoroughly following the parrot bite. The organism identified as the cause of this man’s infection is a naturally occurring aquatic organism found in freshwater and salt water. In humans, it predominantly causes soft tissue infections following exposure to contaminated water. The most common presentation is “fish tank granuloma”, i.e., hand infection following exposure to fish tank water. The majority of cases have a preceding injury to the hand (e.g., bites, abrasions, or puncture wounds) prior to the exposure that allowed entry of the organism through the dermis and into the soft tissue. Based on your reading, what is the etiological agent of this case study?