A 67-year-old male presents with complaints of a burning sen…

A 67-year-old male presents with complaints of a burning sensation and white patches on his tongue and buccal mucosa that can be wiped off, revealing a red, raw surface underneath. He wears full upper and lower dentures and reports that he rarely removes them at night. Medical history includes type 2 diabetes mellitus and recent broad-spectrum antibiotic use for a respiratory infection. A swab of the lesion is sent for culture and microscopy. Which of the following is the MOST appropriate next step in managing this patient?