Dr. Elkhadragy JK is a 32-year-old human immunodeficiency vi…

Dr. Elkhadragy JK is a 32-year-old human immunodeficiency virus (HIV) negative patient presenting to your clinic. He receives a Mantoux skin test that returns positive 2 days later. He was born in the United States and works as a prison guard. He injects heroin on a regular basis. His chest X-ray shows no symptoms of tuberculosis, and his smear culture is negative. What type of drug therapy would be appropriate for this patient?

Dr. He You are working on the infectious disease consultatio…

Dr. He You are working on the infectious disease consultation team in your hospital. As a part of today’s consolation, you are asked to evaluate and make recommendations for antimicrobial therapy on a patient. The patient, DL, is a 47 you man with history of a low cervical spinal cord injury, as a result of a diving accident at the age of 17. He is a paraplegic and has chronic indwelling Foley catheter which drains urine from his bladder. As a result, he has developed recurrent urinary tract infections over the past 10 years. He is readmitted to the hospital with high fever and presumed pyelonephritis yesterday. The preliminary results of his admission urine culture have returned this morning and show greater than 100,000 colonies of gram negative bacillus, confirming a UTI. You review Mr. L’s urine analyses from prior admissions and find multiple infections with gram-negative species that were resistant to ciprofloxacin, levofloxacin, sulfonamides, tetracycline, doxycycline and chloramphenicol.   You will be expected to make recommendation regarding empiric therapy of pyelonephritis. Given your review of the case, which of the following agents would you recommend?