A colleague of ours sends us some data and she’s very confus…

A colleague of ours sends us some data and she’s very confused.  She collected data on the frequencies of a wild type (A) and a lethal recessive (L) allele in a population of Drosophila.  The figure below was the result of plotting her data. She knows that the population clearly evolved over time, but isn’t sure how to explain the pattern seen in the figure.  Explain what evolutionary mechanism(s) could have resulted in the figure above?  Can you determine anything about the population size that she used in his experiment?  Make sure to justify your answers.