A particular pharmaceutical drug requires four reactions, ba…

A particular pharmaceutical drug requires four reactions, back to back, to synthesize in a lab.  You perform each of the four reactions, and obtain the percent yields for each reaction as shown below.  If the percent yield for the overall multistep synthesis is 21.6%, what was the percent yield of reaction 4?   Reaction 1:  81.5% yield Reaction 2:  71.9% yield Reaction 3:  96.4% yield Reaction 4:  ?  (calculate this)