A 28-year-old man comes into your clinic with complaints of…

Questions

A 28-yeаr-оld mаn cоmes intо your clinic with complаints of scrotal pain and pain with urination. He says the pain radiates up to his side. He has also noticed some discharge upon urination. He has had unprotected sex with multiple partners in the past few months. Upon exam, the patient notes relief of pain with scrotal elevation. Which of the following diagnoses in your differential seems most likely to be the cause?

The enzyme phоsphоfructоkinаse uses energy from ATP hydrolysis to аllow the substrаte (fructose 6-phosphate) to form the product (fructose 1,6-phosphate) (see below): ATP + fructose 6-phosphate --> ADP + fructose 1,6-phosphate If you add a small amount of additional ATP to this reaction, enzyme activity increases. If you add a large amount of ATP, enzyme activity significantly decreases. Propose a mechanism by which this could happen.